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   the effectiveness of opioid treatment in patients with chronic cancer pain experiencing breakthrough cancer pain (btcp): biomarker evaluation in the tetrahydrobiopterin pathway  
   
نویسنده wardana ardhian ,waloejo christrijogo sumartono ,putri herdiani sulistyo ,maskoep wiwiek indriyani
منبع journal of medicinal and pharmaceutical chemistry research - 2024 - دوره : 6 - شماره : 11 - صفحه:1643 -1654
چکیده    Chronic pain is a serious issue among cancer patients, with nearly half of all cancer patients experiencing it. approximately 5-20% of these patients report suffering from severe pain that impacts their quality of life, and unresolved chronic pain may even affect the survival of cancer patients. breakthrough cancer pains (btcp) are a major concern for many people around 60% of cancer patients who experience pain. despite efforts to improve pain management, many countries still report errors in assessing and treating this type of pain. opinions about prescribing opioids for cancer pain have changed over time. tetrahydrobiopterin (bh4) regulation may play a part in cancer pain mechanisms. a brief summary of the effectiveness of opioid treatment is provided in this study in chronic cancer pain patients who experience btcp, assessed by biomarkers in bh4 pathway.
کلیدواژه chronic cancer pain ,opioid ,breakthrough cancer pain ,btcp ,tetrahydrobiopterin ,bh4
آدرس airlangga university, faculty of medicine, dr. soetomo general academic hospital, department of anesthesiology and reanimation, indonesia, airlangga university, faculty of medicine, dr. soetomo general academic hospital, department of anesthesiology and reanimation, indonesia, airlangga university, faculty of medicine, dr. soetomo general academic hospital, department of anesthesiology and reanimation, indonesia, airlangga university, faculty of medicine, dr. soetomo general academic hospital, department of anesthesiology and reanimation, indonesia
پست الکترونیکی wiwiekindriyani@yahoo.co.id
 
     
   
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