ultra violet estimation of promethazine hcl in pharmaceutical formulation and industrial waste water sample

A new method is proposed to detect and precisely determining of promethazine hcl. this procedure is easy, straightforward, quick, and cost-effective technique. it is applicable to a wide range of samples, environmental, municipal wastewater, and of course, pharmaceutical preparations (for both tablets and injections). the highest absorbance value was obtained at 248 nm of a uniform content in distilled water. this procedure obeys beer-lambert low at a range of 0.5-15 µg/ml, while the registered molar absorptivity is 2.8x104 l.mol-1.cm-1, whereas the relative standard deviation is less than 2%, and the accuracy (average recovery%) is 100 ± 0.9. this technique was substantiated by sensitivity and precision which confirms appropriation for regular analysis of promethazine hcl in actual samples.