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   medical evaluation of the effectiveness and outcome of regional anesthesia in burn populations to reduce drug use: a systematic review and meta-analysis  
   
نویسنده alizadeh otaghvar hamidreza ,khodakarim nastaran ,molaei amir ,saboury mahdy ,jafarian ali akbar ,delavar marzieh
منبع journal of medicinal and pharmaceutical chemistry research - 2022 - دوره : 4 - شماره : 6 - صفحه:473 -480
چکیده    The results of regional anesthesia (ra) techniques on pain relief and narcotic consumption are challenging and should be evaluated. hence, the purpose of the present article was to evaluate the efficacy and outcome of ra in adult patients with burns to decrease narcotic consumption and pain. the initial search was performed by two blind and independent browsers in electronic databases (pubmed, cochrane library, and embase) until may 2021. for data analysis, after extracting the data of three studies that met the inclusion criteria, the mean and risk difference methods were used with a 95% confidence interval, the fixed-effect model and the mantel-haenszel/inverse variance method were used were calculated for the data. stata software version 16, a faster version of stata, was used for statistical analysis. 24 articles were found in the initial review, the abstracts reviewed by two blind and independent authors. finally, after reviewing the full text of 9 articles, 3 articles were selected. the mean difference of cumulative morphine requirements was -49.01 (md, -49.01 95% ci 56.36, -41.67. p-value=0.00) between continuous ra and control group of cumulative morphine requirements. meta-analysis showed that both ra had statically significantly lower total morphine consumption than the control group. meta-analysis showed ra reduced total morphine consumption and pain.
کلیدواژه regional anesthesia ,burn population ,narcotic consumption ,pain
آدرس iran university of medical sciences, trauma and injury research center, school of medicine, iran, iran university, department of medical oncology and hematology, iran, semnan university of medical sciences, department of surgery, iran, iran university of medical sciences, school of medicine, department of plastic and reconstructive surgery, iran, iran university of medical sciences, pain research center, rasol akram hospital, iran, islamic azad university, tehran medical branch, iran
پست الکترونیکی marziehdelavar@gmail.com
 
     
   
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