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   the most important consideration in clinical usage of curcumin  
   
نویسنده maleki dizaj solmaz ,sharifi simin ,shahi shahriar ,montazersaheb soheila ,salatin sara ,ahmadian elham ,khezri khadijeh ,rahbar saadat yalda ,dalir abdolahinia elaheh ,ghavimi mohammad ali
منبع journal of medicinal and pharmaceutical chemistry research - 2022 - دوره : 4 - شماره : 2 - صفحه:124 -136
چکیده    The main goal of this study was to gather the most critical bioactivities of curcumin, followed by the most essential concerns in its clinical usage and the challenges and potential for its use in modern medical studies. the conducted clinical studies on curcumin showed an effective anti-inflammatory and anti-cancer agent. the search results also revealed that curcumin has poor systemic bioavailability. then, designing new methods to improve its bioavailability has always been interesting. other conditions, such as neurodegenerative disease, cardiovascular disease, and diabetes, should be the subject of additional clinical research in the future. besides, new procedures, such as adjuvants, drug delivery systems, and structural changes should be used in clinical trials of curcumin.
کلیدواژه curcumin ,clinical trials ,anti-inflammatory ,anti-cancer ,drug delivery systems
آدرس tabriz university of medical sciences, student research committee, iran, tabriz university of medical sciences, dental and periodontal research center, iran, tabriz university of medical sciences, dental and periodontal research center, iran, tabriz university of medical sciences, molecular medicine research center, iran, tabriz university of medical sciences, dental and periodontal research center, iran, tabriz university of medical sciences, kidney research center, iran, urmia university of medicalsciences, deputy of food and drug administration, iran, tabriz university of medical sciences, kidney research center, iran, tabriz university of medical sciences, research center for pharmaceutical nanotechnology, biomedicine institute, iran, tabriz university of medical sciences, faculty of dentistry, department of oral and maxillofacial surgery, iran
پست الکترونیکی m_ghavimi@yahoo.com
 
     
   
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