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a simplified green approach for synthesis of arylquinoxalines under solvent-free clay-catalysed conditions
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نویسنده
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khalafy jabbar ,dilmaghani shadi ,etivand nasser ,poursattar marjani ahmad
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منبع
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journal of medicinal and pharmaceutical chemistry research - 2019 - دوره : 1 - شماره : 3 - صفحه:257 -267
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چکیده
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A friendly benign, green, rapid and facile strategy for synthesis a series of arylquinoxalines was achieved by condensation of aromatic 1,2-diamines with arylglyoxals under claycatalyzed as an inexpensive and ecofriendly catalyst using grindstone chemistry. significant decreases in reaction times and high yields have been observed by this green chemistry approach in comparison with previously reported using toxic solvents and reflux conditions. the improved method described herein is economical, environmentally friendly, easilyoperated due to solventfree and easy workup conditions.a friendly benign, green, rapid and facile strategy for synthesis a series of arylquinoxalines was achieved by condensation of aromatic 1,2diamines with arylglyoxals under claycatalyzed as an inexpensive and ecofriendly catalyst using grindstone chemistry. significant decreases in reaction times and high yields have been observed by this green chemistry approach in comparison with previously reported using toxic solvents and reflux conditions. the improved method described herein is economical, environmentally friendly, easilyoperated due to solventfree and easy workup conditions.
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کلیدواژه
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solvent-free; clay catalyst; quinoxalines; 1 ,2-diamines; arylglyoxals; condensation reactions.
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آدرس
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urmia university, faculty of chemistry, department of organic chemistry, iran, urmia university, faculty of chemistry, department of organic chemistry, iran, urmia university, faculty of chemistry, department of organic chemistry, iran, urmia university, faculty of chemistry, department of organic chemistry, iran
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Authors
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