photosensitization of coronene–purine hybrids for photodynamic therapy

Photosensitization properties of coronenepurine (corp) hybrids for photodynamic therapy (pdt) have been investigated in this work. eight hybrid corp models have been designed by the additional of adenine (a) and guanine (g) nucleobase to cor species. the evaluated absorption and emission energies indicated that the singular models are not good at all for pdt process whereas their hybrid models are very much useful for the purpose. although the cora models are very much better for visible region, but the corg models could be also used in the nearinfrared region. the main point of these materials is to generate singlet molecular oxygen, in which all investigated corp hybrids could supply the required energy for triplet to singlet conversion of molecular oxygen. this work has been done based on the advantage of quantum computation for solving the problems in living systems.