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programming of fe-catalyzed cascade knoevenagel-michael-cyclocondensation reaction: create out pseudo acridine derivatives under solvent free conditions
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نویسنده
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khazaei ardeshir ,moosavi-zare ahmad reza ,afshar-hezarkhani hadis ,khakyzadeh vahid
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منبع
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journal of medicinal and pharmaceutical chemistry research - 2020 - دوره : 2 - شماره : 1 - صفحه:27 -34
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چکیده
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Nano-ferrous ferric oxide (nano-fe3o4) was successfully applied as an efficient and heterogeneous catalyst for the synthesis of 1,8-dioxo-decahydroacridines by the condensation reaction of dimedone with aromatic aldehydes and ammonium acetate or aniline derivatives under mild and solvent-free conditions. also, optimization of the reaction condition was investigated using the response surface method {central composite design (ccd)} compared to empirical research.
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کلیدواژه
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nano-fe3o4 ,cascade reaction ,8-dioxo-decahydroacridine ,heterogeneous catalyst
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آدرس
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bu-ali sina university, iran, university of sayyed jamaleddin asadabadi, department of chemistry, iran, bu-ali sina university, faculty of chemistry, iran, k. n. toosi university of technology, department of chemistry, iran
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Authors
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