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   application of [pyridine-1-so3h-2-cooh]cl as an efficient catalyst for the preparation of hexahyroquinolines  
   
نویسنده moosavi-zare ahmad reza ,afshar-hezarkhani hadis
منبع journal of medicinal and pharmaceutical chemistry research - 2020 - دوره : 2 - شماره : 4 - صفحه:465 -474
چکیده    Pyridinium-1-sulfonic acid-2-carboxylic acid chloride {[pyridine-1-so3h-2-cooh]cl} was synthesized and applied as a novel and efficient catalyst for the preparation of hexahydroquinolines by the one-pot multi-component condensation reaction of various aryl aldehydes with dimedone (5,5-dimethylcyclohexane-1,3-dione), β-ketoesters and ammonium acetate under mild and solvent-free conditions. low cost, non toxic nature, simple work-up and excellent yields of products are the main advantages of this work.
کلیدواژه pyridinium-1-sulfonic acid-2-carboxylic acid chloride; hexahydroquinoline; multi-component condensation; β-ketoester; solvent-free
آدرس sayyed jamaleddin asadabadi university, department of chemistry, iran, sayyed jamaleddin asadabadi university, department of chemistry, iran
پست الکترونیکی hadisafshar78@yahoo.com
 
     
   
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