the effect of jollab beverage on fatigue and happiness in patients with multiple sclerosis: a triple-blind randomized clinical trial

Multiple sclerosis (ms) causes different physical and mental symptoms. fatigue and decrease of happiness are the common problems in ms patients. this study aimed to determine the effect of jollab beverage on fatigue and happiness in ms patients. in this triple-blind clinical trial, 70 ms patients visiting the ms association in an urban area of iran were randomly assigned to the two groups by minimization method. the intervention group consumed jollab beverage, including a combination of saffron (crocus sativus l.), rose water (rosa x damascena herrm.) and brown sugar (saccharum officinarum l.), three times a day orally, 15 ml each time for four weeks. the control group consumed placebo similar to the intervention group. fatigue and happiness of the patients were evaluated before and after the intervention using oxford happiness questionnaire and fatigue severity scale. data were analyzed using spss software. based on the results, there was no statistically significant difference between two groups in the mean score of fatigue and happiness before the intervention. but, after the intervention, the mean score of fatigue was lower in the intervention (34.66 ± 7.72) vs. control group (39.12 ± 9.22) ci: 0.26, 8.64, p=0.03). however, the mean score of happiness after the intervention was not statistically significant between the intervention (39.21 ± 17.46) and control ( 45.12 ± 14.30) groups (ci: -1.93, 13.75, p=0.13). according to the results, the use of jollab beverage can reduce the fatigue of ms patients. therefore, use of this beverage can be recommended to the patients by neurologists and ms associations.