unveiling antiarthritic potential of moringa oleifera lam. extract: evaluation and hydroxypropylmethylcellulose-based formulation

Medicinal plants consist of complex chemical compounds that have been acknowledged for their important role in treating persistent human illnesses. this research concentrates on the phyto-physicochemical evaluation of moringa oleifera lam. extract and its in vitro anti-arthritic properties, as determined by inhibiting protein denaturation utilizing varying concentrations of the extract and a standard drug, diclofenac sodium. the study's results revealed a significant in vitro anti-arthritic impact of the extract, with an 85.8% inhibition compared to the standard drug's 99.9% inhibition. furthermore, this research involved creating sustained-release tablets using hydroxypropyl methylcellulose (hpmc)-based formulations and various grades of hydrophilic polymers along with a fixed quantity of a hydrophobic polymer. the manufactured tablets demonstrated favourable sustained-release traits through direct compression, with the mf2 formulation showing a 73.8% cumulative release over 10 hours.