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Long Non-Coding RNAs (lncRNA) Are Key Factors in the Complex Puzzle of Breast Cancer Immunopathogenesis: A Review Study
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نویسنده
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lotfi mohammad ,mahmoudian-sani mohammad-reza ,saeedi-sarqaleh mohammad ,shojaei-moghaddam fatemeh ,saadati-maleki haniyeh ,karimzadeh-soureshjani eleheh ,saadi rasoul ,saeedi-boroujeni ali
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منبع
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immunology and genetics journal - 2023 - دوره : 6 - شماره : 3 - صفحه:91 -102
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چکیده
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Long non-coding rnas (lnc rnas) exert a substantial influence on breast cancer by exerting both positive and negative control over signaling pathways. lncrnas are transcribed similarly to mrna, however they do not undergo the process of translation to become proteins. initially, these rnas were classified as junk rnas since they were thought to lack any practical use. comprehensive research has demonstrated that they play a vital role in the progression of various diseases, including malignancies, allergies, autoimmune and autoinflammatory disorders, infectious diseases, cardiovascular disease, and atherosclerosis. despite multiple efforts, breast cancer continues to be a substantial concern and is one of the most prevalent forms of malignancy, especially among women. recently, researchers have been dedicated to acquiring a deeper understanding of how complex signaling pathways are controlled by lnc-rnas in breast cancer. in the setting of breast cancer, lnc-rnas have a contradictory effect. the objective of this study is to review and categorize previous studies an investigation was conducted to examine the impact of long non-coding rnas on breast cancer. this will improve the capacity to identify topics of research that require further investigation in future studies.
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کلیدواژه
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Breast; Cancer; Immunology; Long-Non-Coding; RNA; Signaling Pathway
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آدرس
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abadan university of medical sciences, student research committee, Iran, ahvaz jundishapur university of medical sciences, thalassemia & hemoglobinopathy research center, health research institute, Iran, abadan university of medical sciences, student research committee, Iran, abadan university of medical sciences, student research committee, Iran, abadan university of medical sciences, student research committee, Iran, abadan university of medical sciences, student research committee, Iran, abadan university of medical sciences, student research committee, Iran, abadan university of medical sciences, student research committee, Iran
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پست الکترونیکی
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ali.saeedi@abadanums.ac.ir
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Authors
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