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   Hepatic Involvement in Eosinophilic Granulomatosis with Polyangiitis  
   
نویسنده mahdavi fatemeh sadat ,dolatshahi elahe ,tabesh saeideh
منبع immunology and genetics journal - 2021 - دوره : 4 - شماره : 2 - صفحه:124 -131
چکیده    We presented a case report of eosinophilic granulomatosis with polyangiitis (egpa) with hepatic involvement which presented itself as multiple nodules in the liver. this confirmed hprevious literature results, which have reported hepatic involvement in egpa. the results of the study showed a 45-year-old female with asthma, presented with polyarthralgia, hypostasis in both hands and skin lesions on the body. lab tests revealed elevated erythrocyte sedimentation rate (esr) and c-reactive protein (crp). the total leukocyte count was 11900 (/ul) with 22% eosinophil. computed tomography (ct) scan of both lungs and liver showed multiple irregular nodules. in the biopsy of the skin lesions, eosinophilic vasculitis was reported. electromyography and nerve conduction velocity (emg-ncv) was compatible to c8-t11 radiculopathy and axonal sensory motor polyneuropathy. according to the tests and biopsies the patient was diagnosed with egpa. although egpa is characterized by asthma, hypereosinophilia and vasculitis, it can be presented with atypical manifestations as well.
کلیدواژه Churg-Strauss Syndrome; Eosinophilic Granulomatosis with Polyangiitis; Hepatic Involvement;Multiple Nodules
آدرس alborz university of medical sciences, student research committee, Iran, alborz university of medical sciences, department of rheumatology, clinical research development unit shahid rajaei, Iran, tehran university of medical sciences, school of public health, department of immunology, Iran
 
     
   
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