a novel sorbent based on metal–organic framework for mercury separation from human serum samples by ultrasound assisted- ionic liquid-solid phase microextraction

In this research, the metal–organic framework (mof) as a solid phase was used for separation mercury [hg (ii)] inhuman serum sample by ultrasound assisted- ionic liquid-solid phase microextraction procedure (usa- il-μ-spe). mercury extracted from serum sample by [zn2 (bdc)2 (dabco)]n as mof at ph=8. hydrophobic ionic liquid ([bmim] [pf6]) was used as solvent trap for hg-mof-nc from the sample solution. the phase of hgmof-nc was back extracted by 0.5 ml of hno3 (0.2 mol l-1) and finally mercury concentration determined with cold vaporatomic absorption spectrometry (cv-aas) after dilution with 0.5 ml of dw. under the optimal conditions, the linear range, limit of detection and preconcentration factor were obtained 0.02– 5.5 µg l^−1, 6.5 ng l^−1 and 9.8 for serum samples, respectively (%rsd<5%). the validation of methodology was confirmed by standard reference materials (srm).