comparative study on the effect of transition metal (zn^2+) and alkaline earth metal (mg^2+) ions on adsorption-release of diclofenac and ibuprofen on nano m-al-ldh as drug carriers

In this project, three nanoscale m-al ldhs, which m is a divalent metal (mg^2+, zn^2+ and/or a mixture of them and ldh = layered double hydroxide) were synthesized by co-precipitation and characterized by general techniques, such as ftir, xrd, fesem, and eds. ldhs have got different physical properties, such as; crystal size, lattice parameters, morphology and drug delivery. these m-al ldhs were used as drug carriers for diclofenac and ibuprofen, which adsorption and release percentages of drugs by them were studied and compared. the results showed that al-ldhs including transition metal (zn^2+) are suitable for drug delivery purposes. as the mixed divalent (zn/mg)-al ldhs are more efficient drug carriers for both diclofenac and ibuprofen drugs.