evaluation of cortisol hormone levels among miscarriage women with toxoplasmosis in suleimani province

Introduction:this study aimed to determine the seroprevalence of toxoplasmosis among women with a history of miscarriage in sulaimani city, iraq, and to assess its association with serum cortisol levels in relation to sociodemographic, clinical, and behavioral factors.materials and methods: a cross-sectional study was conducted on 119 women who experienced miscarriage. sociodemographic information, clinical history, and behavioral data were collected using structured questionnaires. serum samples were tested for anti-toxoplasma igg and igm antibodies as well as cortisol levels through electrochemiluminescence immunoassay (roche cobas e 411). statistical analysis included chi-square tests, spearman correlation, and logistic regression to identify potential risk factors associated with toxoplasma positivity.results: out of 119 women, 28 (23.5%) tested positive for toxoplasma gondii antibodies. the highest prevalence was recorded in women aged 27–36 years (56.0%, p=0.001). educational status showed a significant association, with women having only primary education exhibiting the highest seropositivity (50.0%, p=0.019). no significant differences were found between urban and rural participants (p=0.563). regarding cortisol levels, most participants (74.8%) had values within the normal range, while 7.6% had low and 17.6% had elevated cortisol levels. however, cortisol status was not significantly associated with toxoplasma seropositivity (p=0.765).conclusion: the study demonstrates cortisol levels did not show a significant association with infection status, these findings emphasize the importance of targeted education, awareness, and screening programs. further longitudinal studies are recommended to clarify causal pathways and better prevent pregnancy complications related to toxoplasmosis.