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Prevalence of HepatitisCVirusandIts Occult Infection in Hemodialysis Patients
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نویسنده
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nakhaie mohsen ,taheri ehsan ,charostad javad ,arefinia nasir ,kalantar-neyestanaki davood ,rezaei zadeh rukerd mohammad ,ahmadpour fatemeh ,pourebrahimi mohamad hossein ,ahmadinejad farsangi sara ,shafieipour sara
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منبع
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jundishapur journal of microbiology - 2023 - دوره : 16 - شماره : 5 - صفحه:1 -8
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چکیده
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Background: hepatitis c virus (hcv) is one of the most common infections in hemodialysis patients, which has been associated with increased incidence of morbidity and mortality, particularly in low- and middle-income countries. objectives: the current study aimed to evaluate the hcv antibody, occult hcv infection (oci), and related risk factors among hemodialysis patients. methods: in this cross-sectional study, 100 hemodialysis patients referred to a dialysis center in kerman between december 2021 and march 2022 were assessed for hcv, oci, and their related risk factors. the information related to risk factors was collected by questionnaire, while hcv and oci were detected through serology and real-time polymerase chain reaction (pcr) methods, respectively. results: among the patients participating in the study, 61 were men, and 39 were women. the average age was 58.1 ± 14.9 years in men and 63.6 ± 11.4 years in women. diabetes and hypertension history, old age, low education, self-employment, and urban living weremorecommonin chronic kidney disease patients. the enzyme-linked immunosorbent assay (elisa) revealed 3% positive seroprevalence hcv infection, but only 1% was positive for oci. although no statistically significant relationship was found between the presence of hcv (antibody and oci) and other parameters, all positive hcv cases were identified in patients with low education and freelance employment. conclusions: hemodialysis patients had a low prevalence of hcv antibody and oci. improving various factors and conditions such as lifestyle, occupation, educational level, and dialysis ward and machine disinfection could be beneficial in managing and controlling hemodialysis complications such as hcv and oci.
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کلیدواژه
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chronic Kidney Disease ,Hemodialysis ,Hepatitis C Virus ,Risk Factors ,Iran
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آدرس
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kerman university of medical sciences, gastroenterology and hepatology research center, institute of basic and clinical physiology sciences, Iran, kerman university of medical sciences, physiology research center, institute of neuropharmacology, Iran, shahid-sadoughi university of medical sciences, faculty of medicine, department of microbiology, Iran, jiroft university of medical sciences, student research committee, Iran, kerman university of medical sciences, department of medical microbiology, Iran, kerman university of medical sciences, gastroenterology and hepatology research center, institute of basic and clinical physiology sciences, Iran, lorestan university of medical sciences, nutritional health research center, Iran, kerman university of medical sciences, endocrinology and metabolism research center, institute of basic and clinical physiology sciences, Iran, kerman university of medical sciences, cardiovascular research center, institute of basic and clinical physiology sciences, Iran, kerman university of medical sciences, gastroenterology and hepatology research center, institute of basic and clinical physiology sciences, Iran
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پست الکترونیکی
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shafieipour@kmu.ac.ir
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Authors
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