hsv-1 infection among covid-19 cases with ocular and neurological manifestations

Introduction: sars-cov-2 progression depends on multiple factors, including the compromised immune system and underlying diseases. hsv-1 reactivation in sars-cov-2 infection, more likely in patients with pneumonia and immunodeficiency, may be potentially life-threatening and implicate the prognosis. case presentation: we report two covid-19 cases presenting ocular and neurological manifestations suspicious for hsv-1 encephalitis. conclusions: our study showed hsv-1 ocular manifestation among two covid-19 cases. so, the recurrence of hsv-1 infection probably is related to immune responses during covid-19 pathophysiology.