serotypes, antibiotic resistance genes, and salmonella pathogenicity island genes of salmonella from patients in a hospital in weifang, china

Salmonella is an important foodborne pathogen that causes diarrhea in humans worldwide.objectives: this studyaimedto determine the serotype distribution, antibiotic-resistant genes, andsalmonella pathogenicity island (spi) genes of clinical isolates of salmonella inweifang. methods: a total of 111 salmonella strains were collected from weifang people’s hospital between 2018 and 2020 and subjected to serotyping using the kauffmann-white antigen table. meanwhile, the polymerase chain reaction detected eleven spi1-6 genes andsix antibiotic resistance genes. results: among the 111 salmonella strains, 17 serotypes were identified, with s. typhimurium, s. typhi, and s. enteritidis being themost prevalent. the hila, ssab, ssec, mart, siie, pipb, sopb, and pagnspi1-6 genes were all found during analysis. the inva, misl, and siid genes were detected at 98.2, 97.30, and 97.30% rates, respectively. also, sul2 and blatem were the most prevalent antibiotic resistance genes in this nvestigation, accounting for 68.47 and 21.62% of the total, respectively. conclusions: salmonella isolated from the clinical samples was found to have a diversity of serotypes and possessed various spi and antibiotic resistance genes.