three-year evaluation of <i>pseudomonas aeruginosa</i> bacteremia in patients admitted to a university-affiliated hospital, mashhad, iran

Pseudomonas aeruginosa is an opportunistic gram-negative pathogen that can cause infection in almost any body part.objectives: we aimed to evaluate the characteristics of patients with p. aeruginosa bloodstream infection (bsi).methods: in this cross-sectional study, we retrospectively evaluated the records of 35 patients with p. aeruginosa bsi admitted to the imam reza hospital, mashhad, iran, during 2012 - 2015. age, sex, clinical symptoms, risk factors, underlying diseases, and the antibiogram test results were recorded and compared between nosocomial and community-acquired infection (cai) dead and alive patients using the chi-square test. data were analyzed using spss software, version 21.results: the patients had a mean age of 54.57 ± 20.75 years, with 19 of them being men (54.3%). intubation was only required in the deceased group (n = 19; p = 0.014). tachypnea was more frequent (63.2% vs. 13.2%, p = 0.003), and appropriate treatment was less frequent (27.8% vs. 66.7%; p = 0.02) in the deceased group compared to the control group. most patients with nosocomial infection (n = 24) passed away (66.7%; p = 0.03). all nine patients with a history of burning had a nosocomial infection (p = 0.01). shivering and decreased consciousness were more frequent in patients with cai (both p = 0.03) than in other patients. the antibiogram test results showed high resistance to multiple antibiotics.conclusions: considering the high mortality rate of p. aeruginosa bsi and resistance to multiple antibiotics, it is necessary to pay greater attention to the prevention of nosocomial infection with this pathogen, especially in patients admitted to burn centers and those with specific clinical signs, like tachypnea and leukocytosis.