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successful treatment of postneurosurgical ventriculitis caused by extensively drug-resistant <i>acinetobacter baumannii</i> in a child: case report
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نویسنده
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yang rui ,li fang ,mao weiwei ,wei xin ,liu xinzhu ,guo xiaowen ,luo wentao ,liu yan ,zhang jian
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منبع
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jundishapur journal of microbiology - 2021 - دوره : 14 - شماره : 12 - صفحه:1 -6
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چکیده
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Introduction: the incidence of postneurosurgical acinetobacter baumannii ventriculitis/meningitis, primarily due to drugresistant strains, has increased considerably in recent years. however, limited therapeutic options are available because most antibiotics poorly penetrate the blood-brain barrier, especially in pediatric patients. case presentation: a five-year-old boy developed ventriculitis due to extensively drug-resistant a. baumannii (xdrab) after bilateral frontal external ventricular drainage for spontaneous intraventricular hemorrhage. theboywassafelyandsuccessfully treated with intraventricular (ivt)/intrathecal (ith) polymyxin b together with intravenous tigecycline plus cefoperazone/sulbactam. conclusions: in the present case, postneurosurgical xdrab ventriculitis was closely associated with intraventricular hemorrhage and the placement of external ventricular drainage. ivt/ith polymyxin b combined with intravenous tigecycline and cefoperazone sulbactam could be a therapeutic option against xdrab ventriculitis in children.
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کلیدواژه
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acinetobacter baumannii ,ventriculitis ,pediatrics ,tigecycline ,polymyxin b
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آدرس
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shanghai jiaotong university, school of medicine, xinhua hospital, department of clinical pharmacy, china, shanghai jiaotong university, school of medicine, xinhua hospital, pharmacy management department, china, shanghai jiao tong university, school of medicine, xinhua hospital, department of pediatric neurosurgery, china, shanghai jiaotong university, school of medicine, xinhua hospital, department of clinical pharmacy, china, shanghai jiaotong university, school of medicine, xinhua hospital, department of clinical pharmacy, china, shanghai jiaotong university, school of medicine, xinhua hospital, department of clinical pharmacy, china, shanghai jiaotong university, school of medicine, xinhua hospital, department of clinical pharmacy, china, shanghai jiaotong university, school of medicine, xinhua hospital, department of clinical pharmacy, china, shanghai jiaotong university, school of medicine, xinhua hospital, department of clinical pharmacy, china
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پست الکترونیکی
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zhangjian@xinhuamed.com.cn
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Authors
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