escherichia coli spondylodiscitis: a case report and literature review

Introduction: spondylodiscitis is an infectious inflammatory disease with the involvement of an intervertebral disk and adjacentvertebral bodies. hematogenic spreading of microorganisms from an infectious site is the most common pathophysiologic causeof vertebral osteomyelitis. in this report, a case of escherichia coli spondylodiscitis was described and a review of literature was alsoperformed on cases with e. coli spondylodiscitis.case presentation: a 68-year-old woman referred to our hospital with a 2-month history of intermittent fever, weight loss, and lowback pain. on physical examination, we found obvious bulging with the dimensions of 4  20 cm on about l1 - l4 vertebral area.lumbosacral mri revealed the evidence of l2 - l3 spondylodiscitis. she had positive blood and urine cultures with ciprofloxacinsensitivee. coli and successfully treated without surgery after 8 weeks. nine articles (including 9 patients) regarding e. coli spondylodiscitisor vertebral osteomyelitis have been published from the 1st of january 1985 to the 10th of august 2019. in addition to thesecases, here we report 10th case of e. coli vertebral osteomyelitis. four patients were female and 6 were male. the mean age was 52years with a range of 12 - 69. seven cases had a history of fever, and overall, fever and pain at the site of vertebral involvement werethe most common symptoms.conclusions: in our reported patient, returning to the patient’s medical history and finding a previous urinary tract infection ande. coli bacteremia was crucial in helping to diagnose and treat the patient. in our review, 7 patients had positive blood cultures, afinding that emphasizes the diagnostic value of this test. escherichia coli spondylodiscitis is a relatively rare disease that has usuallya source of urinary tract infection and its clinical signs and symptoms are not distinguishable from vertebral osteomyelitis due toother agents and finally, blood culture can be helpful as a diagnostic method.