postmenopausal choriocarcinoma: case report and literature review

Introduction: choriocarcinoma is a gestational trophoblastic tumor that mainly affects women of childbearing age and rarely occurs in postmenopausal women especially following a long latent period from previous pregnancies. in this case report, we introduce three cases of postmenopausal choriocarcinoma with different clinical signs and symptoms. case report: the first patient was admitted with vaginal wall metastasis, and the second and third cases with postmenopausal vaginal bleeding. they were referred to the department of gynecology-oncology at ghaem hospital in 2015. one case had stage i and two patients stage iii of the disease. treatment was initiated with ema-co regimen according to the histopathology of choriocarcinoma in these patients. complete remission was achieved with chemotherapy for all three cases. concusions: the possibility of choriocarcinoma should be considered as a differential diagnosis in postmenopausal vaginal bleeding and in postmenopausal women with metestatic lesions.