a review of the quality of extant clinical practice guidelines in cancer therapy-induced mucositis

Context: oral mucositis is a common complication in patients with cancer therapy. oral and dental care should be considered as a vital component of caring before, during and after chemotherapy. this study aimed to assess the methodological quality of existing cpgs about cancer therapy-induced mucositis. evidence acquisition: we conducted a review of extant cpgs for the management of mucositis. after screening the guidelines based on inclusion and exclusion criteria, three cpgs were selected and assessed by 5 appraisers by using agree ii instrument. results: assessed cpgs gained the highest scores in the clarity of the presentation domain. scope, purpose (median score, 63.3%), and stakeholder involvement (median score, 54.4%) were found respectively and the lowest scores were in editorial independence domain. the scores in applicability (median score, 30%), rigor of development (median score, 28.8%), and editorial independence (median score, 26.7%) domains were unfavorable. also, every appraiser scored the overall quality of cpgs. conclusions: quality of mucositis cpgs needs to be improved. in otherwords, designing high-quality cpgs in this area is necessary.