Very Late Relapse in Breast Cancer Survivors: a Report of 6 Cases

Abstract background: breast cancer is the most common cancer and the leading cause of cancer death among the women worldwide. the risk of local and distant recurrence is the highest during the first two years following the initial treatment. very late relapse (after 12 years) is uncommon in breast cancer survivors. methods: herein, we report the characteristics and outcomes of 6 such cases of breast cancer. results: the mean age of the patients was 40.1 years (range 30-57) and the mean disease free survival was 19.6 years.conclusion: late relapse is not so common in breast cancer but can occur in any stage. therefore, we suggest life-time follow up for every patient with breast cancer.