association between serum levels of vitamin d and biochemical markers among hematopoietic stem cell transplantation candidates: a cross-sectional study

Background: although vitamin d has been known as an effective substance in bone homeostasis, recent studies indicated a number of other biological properties attributed to vitamin d. patients, who are candidates for hematopoietic stem cell transplantation (hsct), were shown to be at high risk of vitamin d deficiency. objectives: this study aimed at exploring the association between serum levels of vitamin d and biochemical markers among hsct candidates. methods: totally, 214 patients, aged 18 to 65 years, were recruited in the current cross-sectional study. within 24 hours of admission to the bone marrow transplant ward, baseline clinical and demographic characteristics of study participants, serum levels of vitamin d, c-reactive protein (crp), erythrocyte sedimentation rate (esr), hemoglobin, albumin, total protein, crp-albumin ratio (car), and body mass index (bmi) were assessed. participants were divided into 4 groups based on their serum vitamin d levels: subjects with deficient, insufficient, sufficient, and optimal levels of vitamin d. results: across the 4 defined categories of serum vitamin d levels, there was no significant difference in terms of bmi, laboratory parameters, inflammatory factors, and biochemical markers. this lack of significant variation remained in both unadjusted and adjusted models. conclusions: these observations indicate a lack of significant association between serum vitamin d levels and bmi, inflammatory factors, and biochemical markers in individuals undergoing evaluation for hstc.