determination of heavy metals in municipal water network of tehran, iran: a health risk assessment with a focus on carcinogenicity

Background: several contaminants such as trace elements can pollute drinking water sources with subsequent toxic effects on humans. these compounds may also accumulate in target organs and result in carcinogenic reactions. objectives: the concentrations of heavy metals, including arsenic (as), nickel (ni), zinc (zn), aluminum (al), copper (1), cobalt (co), lead (pb), cadmium (cd), iron (cd), tin (2), antimony (sb), chromium (3), and mercury (hg) were aimed to determine in the drinking water of tehran, iran and to assess the carcinogenic and non-carcinogenic risk for consumers. methods: a total of 66 tap water samples were collected from 22 regions of tehran and their heavy metal contents were measured by inductively coupled plasma mass spectrometry (icp-ms). the non-carcinogenic and carcinogenic health risks were calculated, using hazard quotient (hq) and incremental lifetime cancer risk (ilcr), respectively. results: the findings revealed that the mean concentrations of measured elements were lower than the maximum permissible limits established by iranian national standards, united states environmental protection agency (usepa), and the world health organization (who). hq was less than 1 for all metals except cr and ilcr was higher than 1× 10^-4 for cr and cd, which may cause human health risk. conclusions: no carcinogenic effects were posed by heavy metals contamination in the drinking water of tehran; however, the content of cr and cd may cause human health risks because of the high daily intake of tap water throughout the lifetime and the tendency of these metals to accumulate in the human body organs. therefore, implementing ongoing programs to monitor heavy metals in municipal drinking water and applying appropriate corrective actions to prevent the transfer of these pollutants to drinking water is crucial.