evaluation of the effect of perioperative blood sugar level on surgical site infections in patients undergoing total mastectomy

Background: stress hyperglycemia during surgeries has been reported to increase the possibility of surgical site infections (ssis) and worsen the patient’s prognosis. objectives: the aim of the present study was to evaluate the correlation between perioperative blood sugar level and ssis in patients undergoing mastectomy. methods: in this prospective case-control study, 158 female patients undergoing mastectomy were included with diabetes as an exclusion criterion. blood glucose levels were measured in 5 phases for each patient. results: among 158 studied patients, 8 (5.5%) developed ssis. four patients (2.74%) in the control group and 4 patients (50%) in the case group had hyperglycemia in at least one of the stages. logistic regression analysis demonstrated associations between ssi development and any blood glucose value of more than 150 mg/dl. it seems that age, medical history, current smoking, tumor characteristics, previous chemoradiotherapy, surgical duration, administration of prophylactic antibiotics, and other surgical factors have not been significantly correlated with ssi. conclusions: as hyperglycemia is an easily controllable factor, the control of blood sugar levels during the perioperative period is recommended in patients undergoing breast surgeries to decrease ssi rates.