primary splenic lymphoma, a rare yet possible diagnosis: a case report and review of the literature

Introduction: the spleen is subject to a variety of benign and malignant disorders, which can be manifested by nonspecific symptoms or signs. hence, the diagnosis is often made based on radiological examinations and histopathological studies. case presentation: herein we present a case report of a patient with pathologically approved primary splenic lymphoma (psl). the patient was a 63-year-old woman presented with abdominal pain, predominantly in the left upper quadrant, since 1 month. complete blood count (cbc) was normal except for mild anemia. liver enzyme studies showed an elevated alkaline phosphatase level. ultrasound (us) depicted a huge hypoechoic splenic mass and computed tomography (ct) confirmed the lesion to be a hypodense mass partially exophytic from the superior aspect of the spleen measuring up to 124 mm in size. the patient underwent a midline laparotomy and splenectomy and the spleen was sent for histopathological examination, which revealed high-grade b-cell lymphoma measuring 17 × 16 × 10 cm in size with capsular invasion and without any lymphovascular invasion. conclusions: this case report highlights the importance of considering splenic lymphoma as a differential diagnosis, although rare, in a patient with abdominal pain and nonspecific clinical findings.