recurrent hodgkin’s lymphoma with bleeding: a case report

Introduction: one of the rare platelet dysfunction, which is impairment of receptor gpiib/iiia and platelet aggregation defect, is acquired glanzmann’s thrombasthenia. a common cause of this thrombasthenia is an autoantibody or plasma protein inhibitor against a normal gpiib/iiia glycoprotein. case presentation: in this case report, a 28-year-old female with a history of treated hodgkin’s lymphoma presented with a menometrorrhagia and ecchymosis. before that, she had no bleeding history and there was no family history bleeding tendency. laboratory findings revealed bleeding time > 10 minutes, normal partial thromboplastin time (aptt), prothrombin time (pt), fibrinogen, and von willebrand factor. platelet-aggregation studies showed no aggregation to adenosine diphosphate (adp), collagen, and a normal response to ristocetin. the clinical history, medical history, and laboratory findings supported a diagnosis of acquired glanzmann’s thrombasthenia. imaging revealed significant lymph nodes was compatible with recurrent disease. the patient’s menorrhagia and bleeding tendency were controlled by systemic chemotherapy. conclusions: this report shows the association of acquired thrombasthenia with the recurrent hodgkin’s lymphoma, which can be controlled by remission induction chemotherapy.