Primary hepatic diffuse large B cell lymphoma: A case report

In this report we describe a rare case of primary hepatic diffuse large b cell lymphoma in a 67-year-old man who presented with abdominal pain, deteriorated liver function, elevated lactate dehydrogenase. he was found to have diffuse nodular intrahepatic space-occupying lesion with normal α-fetoprotein and carcino-embryogenic antigen. the final diagnosis was made by percutaneous biopsy of the liver as the clinical manifestation not consistent with common liver diseases. the patient was treated with r-chop (rituximab, cyclophosphamide,doxorubicin, vincristine and prednisone) without surgical resection with a favorable response.however, serious complication was occurred after 4 cycles of chemotherapy, and the patient finally died of concurrent acute respiratory distress syndrome.