protective effect of salep on liver

Background: salep is used for various purposes in food industries and traditional medicine. therefore, evaluation of its effect on the liver seems to be necessary. objectives: the aim of this study was to assess salep effect on liver. materials and methods: in this experimental study, various concentrations of salep were intraperitoneally administered to five groups of wistar rats (control, placebo and 20, 40 and 80 mg/kg salep). after one month, liver enzymes and liver tissue were evaluated and compared between different groups. results: significant decreased level of liver enzymes, mda (malondialdehyde) and toc (total oxidation capacity) were found in various concentrations of salep administration. on the other hand, a significant increase was found in tac (total antioxidant capacity) level with various doses of salep. conclusions: elevated level of total protein and albumin and decreased level of liver enzyme by salep extract were found in this study. therefore, this plant may be a useful medicine for patients with liver diseases.