mental health outcomes and sleep status among patients with coronavirus disease 2019

Objective: the immediate impacts of coronavirus disease 2019 (covid-19) on mental health of affected patients and psychiatric morbidities of these patients has been neglected by researchers. we assessed mental health outcomes and sleep status among inpatients and outpatients with covid-19 who were initially referred to our covid-19 clinic in mashhad, iran during april-october 2020. method: in this ethically approved cross-sectional study, 130 patients with confirmed covid-19 who were referred to outpatient clinics and wards of a referral hospital in mashhad, iran were surveyed during april-october 2020. demographic data were collected after obtaining informed written consent. validated persian versions of insomnia severity index (isi), 9-item patient health questionnaire (phq-9), and 7-item generalized anxiety disorder (gad-7) and revised impact of event scale (ies-r) were used as main outcome measures (i.e. status of anxiety, depression, insomnia, and event-related distress). analysis was performed with spss using binary logistic regression. p-values < 0.05 were considered significant. results: overall, 65 inpatients and 65 outpatients were surveyed. the two groups did not significantly defer in terms of insomnia and depression severity, but the outpatients showed higher levels of anxiety (52.3% vs. 24.6%, p = 0.005) and distress compared to inpatients (80.0% vs. 64.6%, p < 0.001). male sex (or = 0.017, 95%ci = 0.000-0.708, p = 0.032) exhibited independent and inverse association with depression in covid-19 patients. being married (or = 0.102, 95% ci = 0.018-0.567, p = 0.009) was independently and inversely associated with anxiety. insomnia was independently associated with event-related distress (or = 7.286, 95%ci = 2.017-26.321, p = 0.002). only depression was independently associated with insomnia (or = 49.655, 95%ci = 2.870-859.127, p = 0.007). conclusion: we found symptoms of psychological distress and anxiety to be more prevalent among outpatients with covd-19 than inpatients. insomnia can be a potential risk factor for adverse mental health outcomes in these patients.