Efficacy of Modified Bioactive Glass For Dentin Remineralization and Obstruction of Dentinal Tubules

Objectives: this study assessed the efficacy of modified bioactive glass (mbg) for dentin remineralization and obstruction of dentinal tubules. materials and methods: thirty-six dentin discs were made from 20 third molars and were stored in 12% lactic acid solution for two weeks to induce demineralization. the samples were divided into three groups (n=12): 1- bg, 2- bg modified with 5% strontium (sr) and 3- bg modified with 10% sr. after applying the bg, the samples were stored in artificial saliva for 7, 14 and 21 days. attenuated total reflection-fourier transform infrared spectroscopy (atr-ftir), x-ray diffraction (xrd) analysis, scanning electron microscopy (sem), and energy-dispersive x-ray (edx) analysis were used to assess remineralization. also, 6 dentin discs were divided into three groups of bg, bg modified with 5% sr and bg modified with 10% sr, to examine tubular occlusion. the discs were etched using 0.5m of edta for two minutes and were stored in artificial saliva for 7 days. changes in dentin surface morphology were evaluated under sem. results: group 3 showed high rates of remineralization at days 7 and 14, although the rate decreased at day 21. group 2 exhibited high rates of remineralization at days 7, 14 and 21. dentinal tubules were partially occluded by bg and bg modified with 5% sr, while they were almost completely obstructed after the use of bg modified with 10% sr. conclusions: strontium increases remineralization. addition of 10% sr to bg enhances apatite formation; however, the apatite dissolves over time. addition of 5% sr to bg stabilizes the apatite lattice and increases the remineralization.