Comparison of Desensitizing Efficacy of an Iranian Dentifrice and a Commercially Available Dentifrice: A Randomized Double-Blinded Controlled Clinical Trial

Objective: the aim of this randomized controlled clinical trial was to investigate the effect of a new iranian toothpaste and a commercially available toothpaste containing desensitizing agent (5% potassium nitrate) on dentine hypersensitivity in a 24-week study.materials and methods: fifty healthy volunteers, who had at least two sensitive root surfaces, completed the study period. the participants were randomly given one of the two toothpastes; iranian (antihypersensitive pooneh) or commercially available (fresh mint sensodyne) toothpaste. visual analogue scales (vass) indi-cating the intensity of tooth hypersensitivity responding to tactile, airblast and cold-water stimuli were examined at baseline and weeks 2, 4, 12 and 24.results: overall, vas scores for tactile, airblast, and cold-water tests significant-ly reduced compared with the baseline in both groups (all p values <0.001).however, there was no significant difference between the two groups regarding the measured parameters.conclusion: this study demonstrated that the iranian dentifrice (antihypersensi-tive pooneh) was as effective as the commercially available one (fresh mint sen-sodyne) in reducing tooth hypersensitivity.