in vitro evaluation of the effect of tricalcium phosphate and gc tooth mouth plus pastes on white spot enamel remineralization.

Bjectives: the main purpose of this study was to compare the remineralizing effects of casein phosphopeptide amorphous calcium phosphate fluoride (cpp-acpf) and tricalcium phosphate (tcp) on artificially induced enamel white spot lesions (wsls). materials and methods: in this in vitro study, 45 sound extracted premolars were immersed in a demineralizing solution (ph=4.5) for 96 hours, and were randomly divided into 3 groups of tcp, mi paste plus, and control. they were exposed to the remineralizing agents for 5 minutes once a day for 30 days. after mounting the teeth in resin blocks and polishing, they underwent a microhardness test at 3 different depths from the enamel surface. data were analyzed by prism software, two-way anova, and tukey’s test (α=0.05). results: the volume percentage of mineral content (vpm) was significantly different among the three groups at 30-, 60- and 90µm depths (p<0.0001). at 30µm depth, cpp-acpf was significantly more effective than tcp (p<0.0001). at 60- and 90µm depths, there was no significant difference between cpp-acpf and tcp (p>0.05)conclusion: both cpp-acpf and tcp had significant efficacy for remineralization of artificially induced enamel wsls under in vitro conditions.