oral rehabilitation of a patient with papillon lefèvre syndrome using fixed full-arch hybrid prostheses supported by four axially loaded implants: a case report with four-year follow-up

This report details the successful prosthetic rehabilitation of a 25-year-old male patient with papillon lefèvre syndrome (pls) using an implant-supported hybrid prosthesis. six implants were placed in the maxilla, and four were placed in the mandibular arch. all implants were inserted axially (non-tilted) and were planned to be loaded after a healing period of 6 months. one implant failed due to graft loss during the healing phase, which was removed and the remaining implants were restored with a hybrid prosthesis after 6 months, using the delayed loading protocol. the patient was followed-up for four years and all the remaining implants successfully integrated and remained fully functional during this period. the prosthesis significantly improved the functional, aesthetic, and psychological well-being of the patient. this case report is the first of its kind to use only four axially placed implants for rehabilitation of a pls patient with a successful four-year follow-up.