a case report of a gingival plasma cell granuloma in a patient on antihypertensive therapy: diagnostic enigma

The aim of the present report was to discuss a unique case of gingival plasma cell granuloma (pcg) in a hypertensive patient on amlodipine therapy. also, we attempt to emphasize the importance of considering primary and advance investigations before making a definite diagnosis. pcg is an extremely rare, reactive, non-neoplastic lesion characterized by the predominance of polyclonal plasma cells. drug-induced gingival overgrowth is a known side effect of amlodipine. a hypertensive 60-year-old female patient reported with a chief complaint of swollen gums and discomfort in the upper front teeth region. a provisional diagnosis of amlodipine-induced gingival overgrowth, combined gingival overgrowth, and fibroma was suggested. surprisingly, histopathology revealed it to be a plasma cell lesion which was confirmed by advanced investigations, thereby establishing a confirmatory diagnosis of pcg.