Measurement and Correlation of Ibuprofen in Supercritical Carbon Dioxide Using Stryjek and Vera Eos

Ibuprofen solubility in supercritical carbon dioxide was measured using a dynamic apparatus at a pressure between 80 and 140 bars at three different temperatures, 308.15, 313.15 and 318.15 k. the mole fraction of ibuprofen in fluid phase was in the range of 0.015 × 10^-3 - 3.261 × 10^-3 at the mentioned operational condition. modified mendez-santiago and teja equation were used to check the consistency of the experimental data. results were correlated using the stryjek and vera equation of state with the van der waals 1-parameter (vdw1) and 2-parameters (vdw2) mixing and combining rules. interaction parameters along with the percentage of the average absolute relative deviation (%aard) were displayed. also, the lydersen group contribution methods were used for predicting the physicochemical and critical properties of the ibuprofen.