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Fabrication of Chitosan-Polyethylene Oxide Electrospun Nanofibrous Mats Containing Green Tea Extract
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نویسنده
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Barzegari A. ,Shariatinia Z.
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منبع
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Iranian Journal Of Chemical Engineering - 2018 - دوره : 15 - شماره : 2 - صفحه:65 -77
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چکیده
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Novel electrospun nanofibrous cs-peo nerve conduits containing 0, 2.5, and 5 % of green tea methanolic extract were developed and characterized by fe-sem, ft-ir, tga/dsc as well as tensile strength analysis. the fe-sem images revealed that all of the nanofibers had an average diameter of ∼80nm. the swelling degree was decreased by increasing the gt amount from 2.5 to 5 %, and this might be attributed to the enhanced interactions of nh2, c(o)nh2, and oh groups of chitosan and peo polymers with the oh groups of gt leading to a less hydrophilic mat surface, thus reducing the attraction by the aqueous medium. moreover, the swelling was at its highest in acidic medium; however, it was decreased in the neutral environment and had the least value within the alkaline medium. the cs-peo-5 % gt exhibited the highest antibacterial activity among three samples examined against both s. aureus and e. coli microorganisms. the cs-peo-5 % gt was proved to be a very suitable candidate to be used as a nerve conduit due to its improved tensile and antibacterial activities
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کلیدواژه
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Nerve Conduit ,Electrospinning ,Green Tea Extract ,Chitosan ,Polyethylene Oxide
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آدرس
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Amirkabir University Of Technology (Tehran Polytechnic), Department Of Chemistry, ایران, Amirkabir University Of Technology (Tehran Polytechnic), Department Of Chemistry, ایران
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پست الکترونیکی
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shariati@aut.ac.ir
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Authors
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