Giant cell fibroma of the buccal mucosa with laser excision: Report of unusual case

Giant cell fibroma (gcf) was described as a new entity of fibrous hyperplastic soft tissue. it seems that stimulus from an unexplained origin can have a role in its etiology. histopathologically gcf is consisted of multinucleated fibroblasts that have oval shape nuclei within the eosinophilic cytoplasm. surgical excision is the treatment of choice and recurrence is very rare. here we report a case of relatively large gcf in a 54-year-old man. gingiva is the common location of gcf. as in our case,it may be mistaken as irritation fibroma especially if it is on the buccal mucosa,the most common location for fibroma. correct diagnosis is based on biopsy and clinical examination to see surface texture roughness. to minimize bleeding because of its large size an excisional biopsy with diod laser was performed under local anesthesia for this patient. © iran j pathol. all rights reserved.