The adverse effects of pregnancies complicated by hemoglobin H (HBH) disease

Hemoglobin (hb) h disease is a moderate form of α- thalassemia resulting from various genetic defects. hbh disease is not necessarily a benign disorder as has been generally thought. we present hereby a 25- year- old iranian pregnant woman whom referred to our hospital for blood transfusion. she exhibited the clinical and hematological manifestation of hbh disease. her father carries a common α-thalassemia deletion while her mother was normal in the hematological profile. the object of this report was to provide information about pregnancies affected by hbh disease. © iran j pathol. all rights reserved.