Primary Malignant Melanoma of the Gastrointestinal Tract: Report of Two Cases

Although gastrointestinal involvement by metastatic malignant melanoma is common butprimary gastrointestinal (gi) melanoma has been reported in rare cases. in this study we reporttwo cases of primary gastrointestinal malignant melanoma that one of them is a known case ofneurofibromatosis type 1(nf1). both cases showed no evidence of any lesions in skin and eye.malignant melanoma of gi tract in patient with neurofibroma is reported with hypothesis of apossible relation between two pathologies. both primary gi melanoma and combination of nf1with primary gi melanoma are rare entities discussed in this article.