epithelial-myoepithelial carcinoma of the palate: report of a case and review of the literatures

Epithelial-myoepithelial carcinoma (emc) is considered as a rare malignant salivary gland neoplasm with good prognosis, low recurrence rate and rare metastasis. here we present a case of epithelial-myoepithelial carcinoma in a 42-year-old female with a swelling of 3-year duration in her palate. histopathologic evaluation of the lesion demonstrated a well-circumscribed, biphasic salivary gland tumor composed of double-layered ductal/glandular structures, composed of small luminal eosinophilic cells and abluminal larger clear myoepithelial cells, and luminal cells were positive for pan-cytokeratin, while the abluminal cells exhibited strong immunoreactivity for p63. ki-67 proliferative index was 1% in abluminal cells. in this article, histopathologic and immunohistochemical features of emc and its mimics are discussed and the previously reported cases of emc in the literature are summarized.