Dietary Total Antioxidant Capacity and Risk of Non-Alcoholic Fatty LiverDisease: A Case‐Control Study

Background: dietary total antioxidant capacity (dtac) has been proposed as a tool for assessingthe intake of antioxidants. this study aimed to assess whether a relationship exists between dietarytotal antioxidant capacity (tac) and the odds of nafld.study design: a case-control study.methods: in this age‐and sex‐matched case‐control study in 2019, patients with nafld andhealthy controls were recruited from a hospital clinic. all participants completed a validated 168‐item food frequency questionnaire, the results of which were subsequently used to generate dietarytac. oxygen radical absorbance capacity values were used to calculate dietary tac.results: altogether, 225 patients with nafld and 450 healthy controls were enrolled. participantswith nafld had a higher mean weight, bmi, energy (p<0.050), and lower physical activity anddtac scores (p<0.050) than the control group. in an adjusted model, participants who were in thehighest quartile of dietary tac had a lower risk of nafld (odds ratio 0.78, 95% ci: 0.67, 0.91).conclusion: a high dtac was related to a decreased risk of nafld. suggest the intake of a dietwith high antioxidant capacity is significant at preventing nafld. increasingly itemizedinvestigations in design of randomized control trials require to reveal more insight into these results.