Assessment of Marhame-Mafasel Pomade Effect on Knee Osteoarthritis with Non-Compliance

Background: osteoarthritis is the most prevalent chronic non-infective joint arthritis. in the present study, the effect of new herbal pomade (marhame-mafasel) on knee osteoarthritis was investigated in a randomized trial. the objective of this study was to assess efficacy of marhame- mafasel pomade,which was consisted of several medic herbs like arnebia euchroma and martricaria chamornilla in primary osteoarthritis of the knee with non-compliance.methods: the 2x2 crossover trial enrolled 42 osteoarthritis patients (marhame-mafasel versus placebo)in 2006. the instrument of data collection was western ontario and mcmaster universities (womac)lk3.1 standard questionnaires. we used conditional estimation to adjust non-compliance effect.results: the participants in each group were 21 patients. about 30 (71.4%) were female. the participants were between 40-76 years old. positive analgesic effect of herbal pomade marhame-mafaselon knee osteoarthritis severity was considerable (p< 0.01 ).after adjusting results to compliance level,the estimators were sharper than crude results.conclusion: herbal joint pomade marhame-mafasel has significant positive analgesic effect on primaryknee osteoarthritis