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   Serological Study for Celiac Disease among Sample of Iraqi Patients  
   
نویسنده waheed mohammed abbas ,al-thwani amina n. ,muhsin mohammed .e. ,kassim rabab
منبع journal of biotechnology research center - 2017 - دوره : 11 - شماره : 2 - صفحه:25 -29
چکیده    This study aimed to detect the celiac disease by using serological markers including aga and ttg. celiac disease (cd) is a complex small intestinal disorder due to a dysregulated immune response to wheat gliadin in children and adults. a total of 412 suspected patients with celiac disease of males and females with age rang (1-48) year, attended central public health laboratory (cphl) baghdad/ iraq during the period between december 2015 - april 2016, only fifty patients with celiac disease with age rang 1-40 were confirmed by two serological test which were anti-gliadin antibodies (aga) and anti-tissue transglutaminase (ttg) conducted by elisa. the results, showed that 73 (17.72 %) of patients were seropositive aga-iga, and 83 (20.15%) were seropositive for aga-igg, whereas 67 (16.27%) were seropositive for both iga and igg of aga test. the seropositive patients for ttg- iga and ttg -igg were 60 (14.56 %), and 69 (16.75 %) respectively. the seropositive for both (ttg -iga and igg) represented 53 (12.87 %) patient.
کلیدواژه Celiac disease (CD) ,autoimmune disease ,Anti-gliadin antibodies (AGA) ,Anti-Tissue transglutaminase (tTG) ,ELISA
آدرس baghdad university, genetic engineering and biotechnology institute, Iraq, university of baghdad, genetic engineering and biotechnology institute, Iraq, iraqi central public health laboratory, Iraq, iraqi central public health laboratory, Iraq
 
     
   
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