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Serological Study for Celiac Disease among Sample of Iraqi Patients
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نویسنده
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waheed mohammed abbas ,al-thwani amina n. ,muhsin mohammed .e. ,kassim rabab
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منبع
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journal of biotechnology research center - 2017 - دوره : 11 - شماره : 2 - صفحه:25 -29
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چکیده
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This study aimed to detect the celiac disease by using serological markers including aga and ttg. celiac disease (cd) is a complex small intestinal disorder due to a dysregulated immune response to wheat gliadin in children and adults. a total of 412 suspected patients with celiac disease of males and females with age rang (1-48) year, attended central public health laboratory (cphl) baghdad/ iraq during the period between december 2015 - april 2016, only fifty patients with celiac disease with age rang 1-40 were confirmed by two serological test which were anti-gliadin antibodies (aga) and anti-tissue transglutaminase (ttg) conducted by elisa. the results, showed that 73 (17.72 %) of patients were seropositive aga-iga, and 83 (20.15%) were seropositive for aga-igg, whereas 67 (16.27%) were seropositive for both iga and igg of aga test. the seropositive patients for ttg- iga and ttg -igg were 60 (14.56 %), and 69 (16.75 %) respectively. the seropositive for both (ttg -iga and igg) represented 53 (12.87 %) patient.
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کلیدواژه
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Celiac disease (CD) ,autoimmune disease ,Anti-gliadin antibodies (AGA) ,Anti-Tissue transglutaminase (tTG) ,ELISA
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آدرس
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baghdad university, genetic engineering and biotechnology institute, Iraq, university of baghdad, genetic engineering and biotechnology institute, Iraq, iraqi central public health laboratory, Iraq, iraqi central public health laboratory, Iraq
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Authors
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