Study of microbial Activity of Some Arylorganomercury ( II ) Derivatives Containing Amino Group on Some Pathogenic Isolated Bacteria

The aim of this study was to evaluate a microbial activity of the three organomercury compounds : 2-amino-5-methylphenyl mercury(ii)chloride 1 , 2-amino-5-bromophenyl mercury(ii)chloride 2 and 2-amino-5- nitrophenyl mercury(ii)chloride 3 which were synthesized and characterized by various physical techniques . it have been reported to have antimicrobial activity against six various bacteria such as gram positive bacteria ( staphylococcus aureus and bacillus subtilis ) and gram negative bacteria ( escherichia coli , klebsiella spp. , salmonella spp. and pseudomonas spp. ) . the concentrations of above compounds 1 , 2 and 3 were ( 0.5 , 0.3 – 0.5 and 0.3 – 0.5 milligram / milliliter ) found to be more effective concentrations than others related with the inhibition zone respectively . the order of antimicrobial activity for the studied compounds were depending on thepower of the drawing group with mercury moiety and amino group abreast in the aromatic skeleton – structure . so , the order is no 2 ( 3 ) > br ( 2 ) > ch 3 ( 1 )