INFLUENCES OF BACTERIA ON ECZEMA : BACTERIAL AND IMMUNE ASPECTS

This study aimed to investigate the most common aerobic bacteria associated with eczema , preparation of bacterial crude antigen from the predominant bacterial isolate as well as determination of total ige and ige specific for bacterial antigen using elisa test. fifty (50) out of ( 80 ) eczematic patients were showing positive skin swab culture with dominance of s. aureus (58%) from both adults and children , corynebacterium , diphtheroid species took the second rank of isolation (22% ) followed by s.epidermedis (16%) and micrococcus species ( 10%). patients with positive swab cultures from both sexes and two age groups showed more ige specific for s. aureus crude antigen (65.5% )than that of s. aureus standard strain . more esosinophil absolute counts were found among patients than control group . we can conclude that bacterial infections associated with eczema makes it more severe via induction of certain mediators ( ige ) in this study and probably through other mediators . s. took the first rank of isolation .