Capability of Lactobacillus acidophilus supernatant to inhibit production of lipase from methicillin-resistant Staphylococcus aureus

The ability of acid supernatants of lactobacillus acidophilus isolated from a vinegar were tested against methicillin resistant staphylococcus aureus (mrsa) with lipolytic activity isolated from acne pimple. results revealed a significant effect of cell free supernatant on mrsa isolates in comparison with control. furthermore, subinhibitory concentrations of acid supernatants found to be very effective in inhibiting the production of lipase from biofilm and planktonic cells of mrsa isolates. what's more, acid supernatants of l. acidophilus showed inhibiting effect on the crude lipase in egg yolk agar plates.