Minor Oral Surgery Procedures in Patients Taking Warfarin: A 5-year retrospective study at Sultan Qaboos University Hospital, Sultanate of Oman

Objectives:minor oral surgery (mos) procedures in warfarinised patients carry the risk of post-operative bleeding. the aim of this study was to conduct a retrospective analysis and to describe the profile of warfarinised patients who underwent mos procedures at sultan qaboos university hospital.methods:a retrospective study of 124 warfarinised patients (41 men and 83 women), who had a pre-operative international normalised ratio (inr) of ≤ 3.5 and underwent different mos procedures under local anaesthesia, without discontinuation of their warfarin therapy, was carried out over a 5-year period from january 2004 to december 2008.results:ninety (72.6%) patients had simple dental extractions, 26 (21%) surgical extractions, 6 (4.8%) soft tissue biopsies and 2 (1.6%) had apicectomies with cyst enucleations. local measures were applied in all patients, which included the use of oxidizing regenerated cellulose haemostatic agent (surgicel) and suturing. a total of eight patients (6.5%), five who had surgical extractions and three who had simple extractions, bled enough post-operatively to require a return to hospital. all cases of post-operative bleeding were managed conservatively by repacking the bleeding site with haemostatic agent and re-suturing without the need for hospital admission.conclusion:minor oral surgery procedures can be safely conducted in warfarinised patients without interruption of warfarin regimen when the pre-operative inr is ≤ 3.5 and appropriate local haemostatic measures are used